Heterocyclic Boron Compounds. I.

Electrochemical oxidation of nitrogen-heterocyclic compounds at boron-doped diamond electrode.

Nitrogen-heterocyclic compounds (NHCs) are toxic and bio-refractory contaminants widely spread in environment. This study investigated electrochemical degradation of NHCs at boron-doped diamond (BDD) anode with particular attention to the effect of different number and position of nitrogen atoms in molecular structure. Five classical NHCs with similar structures including indole (ID), quinoline...

Synthesis of Some New Heterocyclic Compounds with Potential Biological Activity

A series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5H-4-thiazolidinones 2 in glacial acetic acid. The physical and spectral data of the synthesised compounds are determined. The synthesised compounds have been screened for their in vitro ...

Introduction of Medicinal Chemistry & Heterocyclic Compounds

Preparation and Reactions of Heterocyclic Compounds II

Commercial preparation of furan proceeds by way of the aldehyde, furfural, which in turn is generated from pentose containing raw materials like corncobs, as shown in the uppermost equation below. Similar preparations of pyrrole and thiophene are depicted in the second row equations. Equation 1 in the third row illustrates a general preparation of substituted furans, pyrroles and thiophenes fro...

Palladium-catalyzed benzylation of heterocyclic aromatic compounds.

Broadly applicable palladium-catalyzed heteroarene benzylation reactions are described with a focus on the most challenging heterocyclic classes under traditional benzylation techniques such as sulfur-containing heterocycles and those bearing functional groups that would be incompatible with reactions requiring Lewis acids and/or strong bases.